Zebra ZD421 Direct Thermal Printer – Smart, Secure, and Built for What’s Next

The Zebra ZD421 (ZD4A042-D0EM00EZ) is a next-generation 4-inch direct thermal label printer designed for speed, security, and seamless integration. Whether you're upgrading from Zebra’s GK Series or deploying a new fleet, the ZD421 delivers advanced performance with intuitive controls and modular connectivity.

Featuring 203 dpi resolution, USB 2.0, USB Host, and Bluetooth Low Energy 5 (BTLE5), this printer is built to handle high-volume label printing with precision and reliability. Zebra’s Print DNA software suite ensures secure, remote management, while the five-icon LED interface and three-button control panel simplify operation.

Ideal for retail, healthcare, logistics, and manufacturing, the ZD421 is ENERGY STAR® certified and supports Zebra’s full ecosystem of labels, tags, and wristbands. With field-upgradable options and future-ready architecture, it’s the smart choice for growing businesses.

Key Features

• Direct Thermal Printing: No ribbon required—cost-effective and low maintenance.
• High Resolution: 203 dpi for crisp, accurate labels and barcodes.
• Fast Print Speed: Up to 6 inches per second for high-efficiency workflows.
• Modular Connectivity: USB, USB Host, BTLE5.
• Intuitive Interface: 5 LED status icons + 3-button control panel for easy operation.
• Print DNA Suite: Includes PrintSecure, Profile Manager, and ZebraDesigner Essentials.
• Mobile Setup: BLE-enabled for Android/iOS setup via Zebra Printer Setup App.
• Compact & Durable: Dual-wall frame, OpenACCESS™ media loading, ENERGY STAR® certified.
• Media Flexibility: Supports roll-fed, fan-fold, die-cut, continuous, tag stock, and wristbands.
• Backwards Compatible: Supports EPL/ZPL and emulates other printer languages via Virtual Devices.

Technical Specifications